RecruitingNot Applicable

Post-stroke Pain tAN-fMRI

United States24 participantsStarted 2026-01-08

Plain-language summary

The purpose of this study is to explore whether 4 weeks of at-home transcutaneous auricular neurostimulation (tAN) can reduce chronic pain after a stroke. Investigators will recruit up to 24 participants with chronic post-stroke upper extremity pain. The goal is to determine if there is a pain reduction after ear stimulation.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18-80 * Have the capacity and ability to provide one's own consent in English and sign the informed consent document. * Ischemic or hemorrhagic stroke that occurred at least 6 months prior Exclusion Criteria: * Primary intracerebral hematoma or subarachnoid hemorrhage * Documented history of dementia * Documented history of uncontrolled depression or psychiatric disorder * Uncontrolled hypertension despite treatment, specifically SBP (Systolic Blood Pressure) / DBP (Diastolic Blood Pressure) \>=180/100mmHg * Contraindicated for MRI scanning * Pregnancy

What they're measuring

Sensory Threshold

Timeframe: 4 weeks

Pain Threshold

Timeframe: 4 weeks

Pain tolerance

Timeframe: 4 weeks

Trial details

NCT IDNCT07144436

SponsorMedical University of South Carolina

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-06-30

Contact for this trial

Institutional RBFHR Recruitment Contact

843-792-9502 suttonf@musc.edu

View on ClinicalTrials.gov More Post Stroke Pain trials