By InvitationNot Applicable

Selective Versus Non-selective Caries Excavation in MIH Affected Teeth.

Jordan60 participantsStarted 2024-09-01

Plain-language summary

The aim of this study is to compare the clinical and radiographic outcomes of selective versus nonselective caries removal in MIH affected teeth with deep carious lesions using enhanced clinical protocols.

Who can participate

Age range

6 Years – 13 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * The patient age \<13 years old * Non -contributory medical history * Molar affected with MIH as per EAPD diagnostic criteria (White, creamy, or yellow to brownish opacities greater than one millimeter with/without postoperative enamel breakdown). * Deep caries extending\>= 2/3 of dentine but not exposing the pulp on the bitewing radiograph. * The tooth should give positive response to cold sensibility testing. * Clinical diagnosis of normal/ reversible pulpitis * The tooth is restorable, probing pocket depth and mobility are within normal limits. * No signs of pulpal necrosis including sinus tract or swelling * No radiographic evidence of periapical changes indicative of apical periodontitis. Exclusion Criteria: * Medically compromised patient. * Non-restorable tooth. * Clinical diagnosis of irreversible pulpitis. * Signs of pulpal necrosis including sinus tract or swelling. * Teeth indicated for extraction for orthodontic reasons. * Uncooperative children who could not be treated under local anesthesia.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Rate of Radiographic Success

Timeframe: 6,12 months

Rate of Clinical Success

Timeframe: 6,12 months

Trial details

NCT IDNCT07142629

SponsorKing Abdullah University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-08

View on ClinicalTrials.gov More Molar Incisor Hypomineralisation trials

Who can participate

Age range

6 Years – 13 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.