Not Yet RecruitingNot Applicable

The Clinical Trial of Electro-thumbtack Needle on Live Birth Rate in Patients With Ovarian Reserve Dysfunction (DOR)

368 participantsStarted 2025-10-01

Plain-language summary

This study will include 246 patients with ovarian reserve dysfunction (DOR), who will be randomly divided into a treatment group and a control group, with 123 patients in each group. The treatment group will receive electro-thumbtack needle treatment, while the control group will receive placebo electro-thumbtack needle treatment. Both groups will receive a treatment course of 3 menstrual cycles. This study evaluates the effect of electrocautery on the live birth rate of patients with DOR.

Who can participate

Age range

18 Years – 40 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * The age range is 18-40 years old; * Meets the diagnostic criteria for DOR as follows: ① AMH\<1.1 ng/ml; ② 10 U/L \< FSH \< 25U/L or FSH/LH \> 3.6; ③ The total number of follicles (AFC) in both basal sinuses is less than 7. If any two of the above criteria (①②③) are met, it can be diagnosed as DOR. * At least one side of the patient's fallopian tube is unobstructed; * The semen routine examination of the patient's spouse is normal; * Voluntarily sign the informed consent form. Exclusion Criteria: * Chromosomal or genetic abnormalities in either the female or male partner; * Women with blocked fallopian tubes on both sides; * Have a history of ovarian surgery, such as ovarian teratoma or ovarian chocolate cyst surgery; * The female party suffers from uncorrected endocrine disorders such as simple hyperthyroidism or hypothyroidism, hyperprolactinemia, and pancreatic islet dysfunction; * Hormone resistance, diabetes, adrenal diseases, etc; * The woman has a clearly diagnosed autoimmune disease such as systemic lupus erythematosus, rheumatoid arthritis; * Antiphospholipid syndrome, Sjogren's syndrome, Hashimoto's thyroiditis, etc; * The female or male partner has a history of malignant tumors and has received treatment with radiotherapy and chemotherapy; * The woman has received acupuncture and moxibustion or press acupuncture treatment in recent 3 months; * Those who take traditional Chinese medicine decoctions or granules during treatment; * Men with abn…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

live birth rate

Timeframe: 3 months

Trial details

NCT IDNCT07142187

SponsorHuazhong University of Science and Technology

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-10-30

View on ClinicalTrials.gov More Diminished Ovarian Reserve (DOR) trials