The Clinical Trial of Electro-thumbtack Needle on Live Birth Rate in Patients With Ovarian Reserv… (NCT07142187) | Clinical Trial Compass
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The Clinical Trial of Electro-thumbtack Needle on Live Birth Rate in Patients With Ovarian Reserve Dysfunction (DOR)
368 participantsStarted 2025-10-01
Plain-language summary
This study will include 246 patients with ovarian reserve dysfunction (DOR), who will be randomly divided into a treatment group and a control group, with 123 patients in each group. The treatment group will receive electro-thumbtack needle treatment, while the control group will receive placebo electro-thumbtack needle treatment. Both groups will receive a treatment course of 3 menstrual cycles. This study evaluates the effect of electrocautery on the live birth rate of patients with DOR.
Who can participate
Age range18 Years – 40 Years
SexFEMALE
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* The age range is 18-40 years old;
* Meets the diagnostic criteria for DOR as follows: â‘ AMH\<1.1 ng/ml; â‘¡ 10 U/L \< FSH \< 25U/L or FSH/LH \> 3.6; â‘¢ The total number of follicles (AFC) in both basal sinuses is less than 7. If any two of the above criteria (â‘ â‘¡â‘¢) are met, it can be diagnosed as DOR.
* At least one side of the patient's fallopian tube is unobstructed;
* The semen routine examination of the patient's spouse is normal;
* Voluntarily sign the informed consent form.
Exclusion Criteria:
* Chromosomal or genetic abnormalities in either the female or male partner;
* Women with blocked fallopian tubes on both sides;
* Have a history of ovarian surgery, such as ovarian teratoma or ovarian chocolate cyst surgery;
* The female party suffers from uncorrected endocrine disorders such as simple hyperthyroidism or hypothyroidism, hyperprolactinemia, and pancreatic islet dysfunction;
* Hormone resistance, diabetes, adrenal diseases, etc;
* The woman has a clearly diagnosed autoimmune disease such as systemic lupus erythematosus, rheumatoid arthritis;
* Antiphospholipid syndrome, Sjogren's syndrome, Hashimoto's thyroiditis, etc;
* The female or male partner has a history of malignant tumors and has received treatment with radiotherapy and chemotherapy;
* The woman has received acupuncture and moxibustion or press acupuncture treatment in recent 3 months;
* Those who take traditional Chinese medicine decoctions or granules during treatment;
* Men with abn…
What they're measuring
1
live birth rate
Timeframe: 3 months
Trial details
NCT IDNCT07142187
SponsorHuazhong University of Science and Technology