An 'on-eye' UV delivery system for corneal crosslinking can be used safely and effectively to help free presbyopic patients from the need for reading glasses.
Who can participate
Age range
40 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 40-65 years
* Healthy cornea
* Refractive error between +4.0 D and -5.0 D
* Phakic or monofocal pseudophakic (≥6 months post IOL placement)
* Visual acuity correctable by ±0.25 D
Exclusion Criteria:
* Corneal dystrophy, scarring, or prior corneal crosslinking
* Astigmatism \>1.0 D
* Active ocular infection, inflammation, or uncontrolled dry eye
* Advanced glaucoma or diabetic retinopathy
* History of delayed corneal healing
* Pregnancy, breastfeeding, or planning pregnancy during study period
* Certain medications (e.g., isotretinoin)
* Recent participation in other investigational drug/device studies (within 30 days)
* Patients with uncontrolled dry eye or surface disease
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial uses crosslinking to try to reduce refractive error in presbyopia — how does that approach differ from the reading glasses, contact lenses, or LASIK options I might already be considering, and is it worth waiting for this trial versus starting one of those now?
2The trial isn't recruiting yet — given that timeline uncertainty, what does my doctor think about whether it makes sense to keep an eye on this study versus pursuing a treatment that's available today?
3Since this trial is listed as 'Phase NA,' what does that mean for how much is already known about the safety and effectiveness of this specific crosslinking procedure for presbyopia, and are there published results from earlier work my doctor could share with me?
4Corneal crosslinking changes the structure of the eye — are there any risks or permanent changes I should understand before discussing whether I'd even be a candidate for a study like this?
5If I were eventually interested in this trial, what would my doctor want to evaluate about my current eye health, age-related vision changes, or any existing conditions that could affect whether this approach would be appropriate for me to even discuss with the study team?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.