Active — Not RecruitingNot Applicable

Advanced Cardiovascular Management in Major Non-cardiac Surgery.

Italy534 participantsStarted 2024-04-29

Plain-language summary

This is a single center, randomised and controlled clinical triaI whose aim is to predict and treat in advance, intraoperative hypotension episodes. In particular, the aim of the study is to compare the clinical impact of two different hemodynamic strategies based on the use of different monitoring platforms: the Edwards EV1000 equipped with FloTrac sensor and HemoSphere platform equipped with Acumen Hypotension Prediction Index software and Acumen IQ pressure sensor.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Informed Consent as documented by signature (Appendix Informed Consent Form) * Age ≥ 18 years old * Surgical indication for major NCS needing general anesthesia * Anaesthesiologic indication for perioperative arterial cannulation and advanced hemodynamic monitoring Exclusion Criteria: * Informed Refusal as documented by signature (Appendix Informed Consent Form) * Age ≤ 18 years old * Severe aortic valvulopathy * Atrial fibrillation

What they're measuring

MINS and AKI incidence

Timeframe: within 3 and 7 days after surgery

Trial details

NCT IDNCT07134530

SponsorFondazione IRCCS Policlinico San Matteo di Pavia

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04

View on ClinicalTrials.gov More Intraoperative Hypotension trials