AI-Guided Treatment Planning in Orthodontic Patients With Missing Upper Lateral Incisors (NCT07133867) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
AI-Guided Treatment Planning in Orthodontic Patients With Missing Upper Lateral Incisors
Egypt110 participantsStarted 2024-03-28
Plain-language summary
This pilot study aims to evaluate the diagnostic accuracy of artificial intelligence (AI) in orthodontic treatment planning for patients with congenitally missing upper lateral incisors. The study compares AI-generated treatment recommendations with decisions made by experienced orthodontists regarding two main treatment options: space closure and prosthetic replacement. Orthodontic records, including intraoral and extraoral photographs, panoramic radiographs, and cephalometric analyses, will be collected for each case. Two orthodontists with over 10 years of clinical experience will independently evaluate each case using a treatment decision checklist with predefined cutoff points. AI predictions will then be compared to orthodontists' consensus decisions to determine agreement rates and accuracy. The findings will provide insight into the potential role of AI in supporting complex orthodontic decision-making.
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients diagnosed with unilateral or bilateral congenitally missing maxillary lateral incisors (confirmed by panoramic radiograph).
* Availability of complete diagnostic records: intraoral photographs, extraoral photographs, cephalometric radiograph, and panoramic radiograph.
* Cases either finished (completed orthodontic treatment) or unfinished (under treatment).
* No prior prosthetic replacement for the missing lateral incisors before initial orthodontic planning.
Exclusion Criteria:
* Patients with craniofacial syndromes or cleft lip/palate.
* Cases with incomplete or poor-quality diagnostic records.
* History of previous orthodontic treatment unrelated to the current missing lateral incisor case.
* Multiple missing teeth outside the upper lateral incisor region that could affect treatment planning.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Diagnostic Accuracy of AI in Orthodontic Treatment Planning for Missing Maxillary Lateral Incisors