Not Yet RecruitingNot Applicable

Validation of New Biomarkers for Predicting No-Reflow in STEMI Patients Undergoing Primary PCI

114 participantsStarted 2025-09-01

Plain-language summary

To evaluate the diagnostic value of the selected emerging biomarkers in predicting the no-reflow phenomenon among patients presenting with STEMI undergoing primary PCI. These biomarkers include: HbA1c/C-peptide ratio Albumin-bilirubin (ALBI) score. Neutrophil/HDL ratio

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 18 years * Suitable for and undergoing timely primary PCI based on symptoms and clinical judgment * Provision of informed consent Exclusion Criteria: * History of previous MI, PCI, or CABG * Known chronic inflammatory or autoimmune diseases * Advanced renal or hepatic failure * Active infection or malignancy at presentation * Incomplete data or refusal to consent

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

HbA1c/C-peptide ratio predictive accuracy for no-reflow phenomenon

Timeframe: Baseline (prior to PCI)

Albumin-bilirubin (ALBI) score predictive accuracy for no-reflow phenomenon

Timeframe: Baseline (prior to PCI)

Neutrophil/HDL ratio predictive accuracy for no-reflow phenomenon

Timeframe: Baseline (prior to PCI)

Trial details

NCT IDNCT07132489

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-09-01

Contact for this trial

Hossam E. A. Abdelhafiz

00201143999651 Hossamalaa203040@gmail.com

View on ClinicalTrials.gov More Myocardial Infarction trials

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

HbA1c/C-peptide ratio predictive accuracy for no-reflow phenomenon

Timeframe: Baseline (prior to PCI)

Albumin-bilirubin (ALBI) score predictive accuracy for no-reflow phenomenon

Timeframe: Baseline (prior to PCI)

Neutrophil/HDL ratio predictive accuracy for no-reflow phenomenon

Timeframe: Baseline (prior to PCI)