RecruitingNot Applicable

Treatment Monitoring for NTM Infections With a Symptom Diary

Germany200 participantsStarted 2025-07-11

Plain-language summary

The primary aim of the study is to investigate the correlation between patient-reported symptoms recorded in the diary and the microbiological and radiological disease course in patients with pulmonary infections caused by nontuberculous mycobacteria (NTM).

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Pulmonary NTM infection according to ATS/IDSA criteria (1) * Age ≥ 18 years * Ability to provide informed consent * Willingness to participate in the study AND * Clinical decision to initiate antimicrobial therapy as part of routine care * Cohort 1 OR * Clinical decision against antimicrobial therapy as part of routine care * Cohort 2 Exclusion Criteria: * Lack of ability to provide informed consent * Language barriers that prevent completion of the diary * Antimicrobial therapy for the NTM infection already initiated

What they're measuring

Degree of correlation of the symptom diary with radiology

Timeframe: 6 months from enrolement

Degree of correlation of the symptom diary with microbiology

Timeframe: 6 months from enrolment

Degree of correlation of the symptom diary with microbiology

Timeframe: 6 months from enrolment

Degree of correlation of the symptom diary with microbiology

Timeframe: 6 months from enrolment

Trial details

NCT IDNCT07131774

SponsorResearch Center Borstel

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-06

Contact for this trial

Thomas Theo Brehm, Dr. med.

+49 4537 188 2905 tbrehm@fz-borstel.de

View on ClinicalTrials.gov More Non-Tuberculous Mycobacterial (NTM) Infections trials