Impact of Aortic Geometry on Vascular Remodeling After Stent Implantation in Coarctation of the A… (NCT07131111) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Impact of Aortic Geometry on Vascular Remodeling After Stent Implantation in Coarctation of the Aorta
Egypt50 participantsStarted 2025-09-01
Plain-language summary
This study aims to assess:
1. Aortic geometrical changes and their relationship to hypertension and cardiovascular events.
2. Aortic geometrical differences between healthy individuals and patients with repaired coarctation of the aorta.
Who can participate
Age range
12 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Age ≥ 12 years.
Diagnosed with native or recurrent coarctation of the aorta.
Transcatheter systolic pressure gradient ≥ 20 mmHg.
Body weight ≥ 20 kg.
Availability of pre- and post-stenting CT aortography data.
Exclusion Criteria:
Patients with obstructive lesion of LVOT or aortic valve dysfunction greater than moderate (requiring surgical intervention)..
Patients with other causes of secondary hypertension.
Associated complex congenital heart defects (aside from simple septal defects and patent ductus arteriosus)
Genetic syndromes
Connective tissue disorder
History of surgery involving the aortic root or ascending aorta.
Incomplete imaging or missing data relevant to the study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.