By InvitationNot Applicable

Incentives and Long-Acting Injectable Adherence After Involuntary Hospitalization

United States1,000 participantsStarted 2026-03-09

Plain-language summary

This study is a randomized controlled trial evaluating the impact of financial incentives on medication adherence among individuals with schizophrenia, schizoaffective disorder, or bipolar disorder and/or co-occurring substance use disorder who are recently discharged from involuntary hospitalization or are at high risk of future involuntary hospitalization. Participants will be randomized to receive financial incentives for adherence to long-acting injectable medications or to a control group.

Who can participate

Age range18 Years – 65 Years

SexALL

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Inclusion Criteria: * Diagnosis of schizophrenia, schizoaffective disorder, and/or bipolar disorder * Recent (within 12 months) involuntary hospitalization or high risk of future hospitalization * Eligible for medication (antipsychotic or SUD-related) with an LAI formulation * Allegheny County, PA resident * Receiving or assigned to treatment at clinics participating in this study Exclusion Criteria: * Lack of injectable formulation for prescribed medication * Aged under 18 or 65 or older

What they're measuring

Adherence to antipsychotic medication

Timeframe: From start of study to end of study 12 months later; for follow-up, for 12 months after end of study.

Involuntary hospitalization

Timeframe: From start of study to end of study 12 months later; for follow-up, for 12 months after end of study.

Trial details

NCT IDNCT07130500

SponsorStanford University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-03

View on ClinicalTrials.gov More Schizophrenia Disorder trials