Biomarker pAtterns Reflecting habITual fOod iNtakE: the BARITONE Project
Sweden100 participantsStarted 2025-09-15
Plain-language summary
The BARITONE study's overall aim is to understand how our eating habits affect our long-term health. By identifying biological traces in blood, urine and other samples - so-called biomarkers - the investigators want to be able to see what people actually eat, such as protein from different food sources as well as fruit, berries and vegetables. These biomarkers could in the future improve the possibilities to find out how dietary habits affect the risk of disease.
The investigators are targeting healthy people who are interested in participating in research on biomarkers of dietary intake. The research is divided into a cross-sectional study, where the investigators collect data on the participant's usual dietary intake, health and biological samples at the screening visit, and an cross over intervention study that involves eating three different diets (meat, fish, vegetarian) for a total of 3 weeks with one week wash-out in between.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Healthy adult
* 18-65 years
* BMI 18.5-30 kg/m²
* Willing to consume the three diets i.e. meat, fish, and vegetarian
* Understands Swedish
* Low intake of vegetables, fruit and berries (lowest tertile of screened participants, estimated \<100g day) or high intake of vegetables, fruit and berries (highest tertile of screened participants, estimated \>400g day)
Exclusion Criteria:
* Pregnancy and lactation
* Diagnosis of cancer or other life threatening diseases
* Diagnosis of metabolic or food related diseases inluding diabetes, inflammatory bowel disease, hypothyroidism or celiak disease.
* Medication that influences the metabolism such as blood lipid lowering medication, insulin, etc.
* Use of drugs other than medication and alcohol
* Nicotine use (snuff, vaping and smoking)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.