Microneedle Treatment of Chronic Phase Peyronie's Disease: A Pilot Clinical Trial

Inclusion Criteria: * 1\. Healthy males aged 18 or older in a stable relationship with a female partner/spouse (for at least 3 months and willing to have vaginal intercourse with their female partner/spouse).Non heterosexual men are also included; however they need not fill out the PDQ questionnaire as it pertains to those having intercourse with females. 2\. Diagnosis of PD for at least 12 months with evidence of stable disease as determined by the investigator (i.e. no change in penile curve for at least 6 months and absence of pain). 3\. Penile curvature of 30º-90º in the dorsal, lateral, or dorsal/lateral plane (must be possible to delineate the single plane of maximal curvature for evaluation) 4\. Signed informed IRB-approved consent agreement; signed authorization form to allow disclosure of protected information. 5\. Ability to read, complete, and understand the various rating instruments in English. Exclusion Criteria: * 1\. Penile curvature of \<30º or \>90º 2\. Any conditions affecting the penis such as a chordee in the presence or absence of hypospadias; thrombosis of the dorsal penile artery; infiltration by a benign or malignant mass or an infectious agent; ventral curvature from any cause; presence of an active sexually transmitted disease. 3\. Failure to achieve a sufficient 8/10 erection (after prostaglandin E or Trimix administration), in the opinion of the investigator, to accurately measure the penile deformity. 4\. Calcified plaque …