CompletedNot Applicable

The Effect of an Suction Toothbrush on the Development of Ventilator-Associated Pneumonia

Turkey (Türkiye)111 participantsStarted 2025-02-01

Plain-language summary

Literature suggests that suction toothbrushes may improve oral care in intubated patients by facilitating secretion removal and reducing microaspiration. This could decrease the need for endotracheal suctioning and lower the risk of ventilator-associated pneumonia (VAP). Therefore, this study aimed to examine the effect of a suction toothbrush on the development of VAP in intubated patients.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Patients * who aged over 18 years * who underwent orotracheal intubation after admission to the ICU, * who had no known pneumonia or diagnosis of pneumonia at the time of intubation, * who were intubated for more than 48 hours, * who had no microorganisms detected in the tracheal aspirate within the first 48 hours, * who had no lesions on the oral mucous membrane before intubation, * who had no known allergy to chlorhexidine were included in the study. Exclusion Criteria: Patients * who under 18 years of age, * those with a tracheostomy, * those were intubated for less than 48 hours, * those with microorganisms detected in their tracheal aspirate within the first 48 hours, * those who underwent reintubation, * those were pregnant, * those with lesions in the oral mucosa during intensive care admission, * those with bleeding coagulation disorders or thrombocytopenia, * those admitted to intensive care from an external institution while intubated, and those with a known chlorhexidine allergy were excluded from the study.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

The ventilatory associated pneumonia (VAP)

Timeframe: Patients were included 48 hours after admission to the intensive care unit and intubation. After 48 hours of intubation, the development of VAP will be considered as a positive.

Trial details

NCT IDNCT07125495

SponsorKoç University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-07-01

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