RecruitingNot Applicable

Neutrophil to Lymphocyte Ratio in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Egypt190 participantsStarted 2025-05-20

Plain-language summary

Chronic obstructive pulmonary disease (COPD) stands as one of the leading causes of mortality worldwide. Acute exacerbations of COPD (AECOPD) lead to rapid respiratory function decline and worsened disease status. Despite recent studies, the ability of the neutrophil-to-lymphocyte ratio (NLR) to predict outcomes in patients with COPD remains controversial. It remains controversial whether NLR can predict clinical outcomes in hospitalized patients with AECOPD. Therefore, this study was conducted to investigate the predictive value of NLR for severity, adverse outcomes in hospitalized patients with AECOPD, and predicting treatment response in patients with AECOPD

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged 18 and above, Patients who will be admitted at the Chest department, Ain-Shams University Hospitals, diagnosed with AECOPD based on the Global Initiative for Chronic Obstructive Lung Disease 2024 criteria Exclusion Criteria: * Patients who refused treatment. * COPD patients with Malignancy, hematological disorders

What they're measuring

The ratio of neutrophils to lymphocytes in (%) in the CBC

Timeframe: baseline

Trial details

NCT IDNCT07125352

SponsorAin Shams University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-12

Contact for this trial

Hieba G Ezzelregal, MD

01002041611 hiebagamal24@med.asu.edu.eg

View on ClinicalTrials.gov More Chronic Obstructive Pulmonary Disease Exacerbation trials