Not Yet RecruitingNot Applicable

High-resolution Magnetic Resonance Vessel Wall Imaging of Plaques

China605 participantsStarted 2025-08-10

Plain-language summary

The primary objective of this study is to investigate the predictive value of High-resolution magnetic resonance vessel wall imaging for future stroke occurrence in patients with moderate to severe intracranial and extracranial artery stenosis. The secondary objective is to explore the predictive value of baseline high-resolution magnetic resonance vessel wall imaging for plaque progression.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * At least 18 years old; * Medium or severe stenosis of the internal carotid artery, middle cerebral artery, V4 segment of vertebral artery or basilar artery \[stenosis degree: 50% \~ 99%, confirmed by CTA, MRA or DSA\]; * Accept high resolution magnetic resonance angiography; The patient or the legal representative of the patient is able and willing to sign an informed consent form Exclusion Criteria: * Non-atherosclerotic intracranial and extracranial artery stenosis, such as dissection, smoke disease, etc.; * There are contraindications to MRI, such as claustrophobia, metal implants, etc.; * Renal insufficiency, elevated serum creatinine (more than twice the upper limit of normal); * Patients with severe cardiopulmonary diseases were considered unsuitable for this study; * Gadolinium contrast agent allergy; * Participants who were unable to complete the study due to mental illness, cognitive or emotional disorder.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Lumen Stenosis Rate

Timeframe: 2024.08-2027.12

Identify different plaque components

Timeframe: 2024.08-2027.12

Trial details

NCT IDNCT07125339

SponsorShanghai Jiao Tong University Affiliated Sixth People's Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-06-01

Contact for this trial

Yueqi Zhu, MD

0086-21-64844183 zhuyueqi@hotmail.com

View on ClinicalTrials.gov More Intracranial Atherosclerotic Stenosis trials