Not Yet RecruitingPhase 3

Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences

United States50 participantsStarted 2026-05

Plain-language summary

Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque. Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's Cavity Protection toothpaste (P). Both groups utilize their assigned dentifrice for 6 weeks. A pre and post-assessment measures the Gingival Index (GI) and Plaque Index (PI) and Decayed, Missing and Filled Teeth (DMFT). A questionnaire on the use of the product is distributed at the end of the study.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Subjects are 18 years or older;
✓. Subjects who will comply with study protocol;
✓. Subjects who can read and understand the consent form;
✓. Subjects available during the study period;
✓. Subjects have more than 20 teeth.

What they're measuring

Plaque Index Score at Baseline

Timeframe: Change between baseline at visit 1 and visit 2, six weeks post baseline

Gingival Index Score at Baseline

Timeframe: Change between baseline at visit 1 and visit 2, six weeks post baseline

Trial details

NCT IDNCT07124533

SponsorLoma Linda University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12

Contact for this trial

So Ran Kwon, DDS, MS, PhD

909 558 5118 sorankwon@llu.edu

View on ClinicalTrials.gov More Gingival Inflammation trials