Regional Anesthesia in TKA: Impact on Postoperative Joint Motion and Patient Satisfaction (NCT07124494) | Clinical Trial Compass
RecruitingNot Applicable
Regional Anesthesia in TKA: Impact on Postoperative Joint Motion and Patient Satisfaction
Turkey (Türkiye)30 participantsStarted 2025-08-05
Plain-language summary
This is a single-center, prospective, randomized controlled trial aiming to evaluate the effects of different regional anesthesia/analgesia techniques on postoperative knee range of motion (ROM) and patient satisfaction following total knee arthroplasty (TKA). Ninety patients undergoing elective TKA under spinal anesthesia will be randomly assigned to one of three groups: 1) spinal anesthesia with epidural catheter, 2) spinal anesthesia followed by adductor canal catheterization, and 3) spinal anesthesia with multimodal intravenous analgesia. The primary outcome is postoperative knee joint ROM measured on postoperative days 1, 2, and 3. Secondary outcomes include patient satisfaction, Oxford Knee Score, postoperative opioid consumption, and VAS scores. The study is conducted at Konya City Hospital and will be completed over a 6-month period.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
* Minimum Age: 18 Years
* Maximum Age: None
* Sex: All
* Gender Based: No
* Accepts Healthy Volunteers: No
* Inclusion Criteria:
* Scheduled for primary total knee arthroplasty
* Age ≥ 18 years
* American Society of Anesthesiologists (ASA) physical status I-III
* Accepting neuraxial anesthesia
* Exclusion Criteria:
* Skin infection at the planned injection site
* Sepsis
* Coagulopathy
* Refusal of neuraxial anesthesia
* Severe hypovolemia
* Demyelinating central nervous system disease
* Age under 18 years
* Illiterate in Turkish
* Non-cooperative patients
* Known allergy or hypersensitivity to bupivacaine
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Postoperative Knee Range of Motion (ROM)
Timeframe: Postoperative day 1, day 3, day 7, and day 90 after surgery.