Oregano and Basil Leaves and Coronary Artery Disease (NCT07123181) | Clinical Trial Compass
RecruitingNot Applicable
Oregano and Basil Leaves and Coronary Artery Disease
Iran70 participantsStarted 2025-09-01
Plain-language summary
The present study will examine the effects of increasing dietary polyphenol intake by consumption of oregano and basil leaves, on plasma inflammatory and lipid factors and total urinary polyphenol levels in patients who have recently had unstable angina.
Who can participate
Age range
30 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients diagnosed with unstable angina
Exclusion Criteria:
* Patients diagnosed with STEMI
* Patients undergoing coronary artery bypass grafting
* Liver cirrhosis and advanced chronic kidney disease (CKD 5)
* Having known inflammatory and autoimmune diseases, such as inflammatory bowel disease (IBD) and rheumatoid arthritis, or taking glucocorticoid medications
* Pregnancy or breastfeeding
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial uses oregano and basil leaves as a treatment for acute coronary syndrome and unstable angina — how does using herbal supplements compare to the standard medications I'm already being offered, and could it interfere with any of my current heart treatments?
2Since this trial is listed as 'Phase NA,' what does that mean for how much safety and effectiveness data already exists on using these herbs medicinally for someone in my situation with unstable angina?
3The trial is measuring inflammation markers and blood lipid levels — do my current test results suggest those are areas where I personally might benefit from being in a study like this?
4Unstable angina can be a serious and fast-moving condition — would participating in this trial delay or replace any standard care I should be receiving right now, and is that a risk worth taking?
5If I were to discuss joining this trial with you, what would the actual day-to-day commitment look like, and are there any known risks from taking concentrated oregano or basil supplements alongside my heart medications?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Plasma inflammatory biomarkers
Timeframe: At the beginning of the study and two months later
2
Plasma lipids
Timeframe: At the beginning of the study and two months later
Trial details
NCT IDNCT07123181
SponsorShahid Beheshti University of Medical Sciences