RecruitingNot Applicable

Real-World Study on Chinese Medicine for Treating Chikungunya Fever

China600 participantsStarted 2025-07-26

Plain-language summary

This study aims to evaluate the effectiveness and safety of Chinese Medicine-used alone or combined with Western medicine-in treating chikungunya fever, a mosquito-borne viral disease causing fever, rash, and severe joint pain. With recent outbreaks in China (including over 3,000 cases in Foshan, Guangdong) and no specific antiviral treatment available, Chinese medicine may offer a valuable therapeutic option based on its symptom-relief and syndrome-specific approach.

Who can participate

SexALL

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Inclusion criteria

✓. Meets the suspected or confirmed diagnostic criteria for chikungunya fever;
✓. Symptom onset ≤3 days before enrollment;
✓. Actual prescribed treatment aligns with the study's group assignment (TCM, Western medicine, or combined therapy)
✓. Signed informed consent form

Exclusion criteria

✕. Severe chikungunya fever;
✕. Participation in another drug clinical trial within the past 3 months;
✕. Any other condition deemed by the investigator as unsuitable for enrollment.

What they're measuring

Change in Rash Severity Assessed by Modified Eczema Area and Severity Index (mEASI)

Timeframe: From the enrollment to the end of the observation on the 28th day

Proportion of Participants Achieving Clinically Significant Improvement in Joint Symptoms Assessed by Disease Activity Score 44 (DAS44)

Timeframe: From enrollment to the end of the observation on the 28th day.

Time to Complete Fever Resolution

Timeframe: From the enrollment to the end of the observation on the 28th day.

Trial details

NCT IDNCT07120724

SponsorGuangzhou University of Traditional Chinese Medicine

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-07-26

View on ClinicalTrials.gov More Chikungunya Fever trials