Clinical Effectiveness of Bioactive Silica Based With Calcium Toothpaste

Inclusion Criteria: * Patient with non cavitated carious WSL in at least one upper or lower tooth. * Teeth with active non cavitated white spot carious lesions on the cervical one third of the facial or lingual surfaces. Teeth with initial carious lesions with score 1 or 2 according to The International Caries Detection and Assessment System (ICDAS). • Teeth with Diagnodent values between 14-20 that refers to early enamel caries. Exclusion Criteria: Patients with known allergies or adverse reactions to any ingredient of the tested materials. • Systematic disease and/ or physical disabilities that may affect participation. • Patients with white spots due to congenital reasons e.g. enamel hypomineralization. • Pregnant females with frequent vomiting attacks. • Smokers. • Excessive dietary or environmental exposure to acids. * Presence of surface cavitation or restorations .