RecruitingNot Applicable

Integrating HIV Prevention With TB Household Contact Evaluation in Uganda

Uganda2,480 participantsStarted 2025-12-10

Plain-language summary

This household randomized implementation study assesses the implementation and effectiveness of home-based HIV self- testing and PrEP initiation versus standard clinic referral for PrEP initiation during modified standard-of-care (modified SOC) household TB contact investigation in Uganda. It uses qualitative methods to evaluate the process of implementing the intervention and a health economic evaluation to assess the financial sustainability of this strategy.

Who can participate

Age range15 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Person with pulmonary TB OR live in a household with someone with pulmonary TB being treated at one of the participating health facilities * Household includes ≥2 persons * Age 15 years and older * Willingness to participate in study procedures Exclusion Criteria: * Lives in a congregate setting (e.g., dormitory or jail) * Lives outside the study area * Any other condition that, in the opinion of the Investigator/designee, could preclude informed consent, make study participation unsafe, or otherwise interfere with achieving study objectives

What they're measuring

PrEP uptake

Timeframe: From enrollment to the one-month follow-up visit

Trial details

NCT IDNCT07119359

SponsorUniversity of Washington

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-08-01

Contact for this trial

Jennifer M Ross, MD, MPH

206 543-9192 jross3@uw.edu

View on ClinicalTrials.gov More Tuberculosis (TB) trials