Memory Deterioration in Alzheimer Disease (NCT07118137) | Clinical Trial Compass
RecruitingNot Applicable
Memory Deterioration in Alzheimer Disease
Norway30 participantsStarted 2023-10-15
Plain-language summary
Semantic AD
Who can participate
Age range
55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Confirmed diagnosis based on current ICD criteria for AD or MCI .
* \>55years.
* Norwegian native speaker
* Lives at home and not in a health institution
Exclusion Criteria:
* Patients with severe cognitive impairment that prevents assessment with the selected modalities (planned cut-off: CDR \> 2).
* Presence of brain tumors.
* History of traumatic brain injury.
* History of cranial surgery.
* Contraindications to the selected imaging modalities (e.g., 7T MRI or EEG).
* Diagnosis of other neurodegenerative diseases such as Parkinson's disease or ALS.
7T MRI contraindications:
* Large tattoos close to the head region, permanent makeup or unremoveable piercings
* Certain models of pacemakers (if pacemaker implantet, MRI physicist at 7T-lab will be conferred)
* Implantet metal in body (clips, stents, prothesis, skrews, plates, teeth etc.)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Understand which individual differences are observed among patients with Alzheimer's disease (AD).
Timeframe: From enrollment to end of follow-up at 1 year.
2
Compare changes in the brain, blood, and stool samples between dementia patients and healthy controls.
Timeframe: From project enrollment to end of follow-up at 1 year.
Trial details
NCT IDNCT07118137
SponsorNorwegian University of Science and Technology