RecruitingNot Applicable

Biomarkers in Ankylosing Spondylitis

Turkey (Türkiye)160 participantsStarted 2026-01-15

Plain-language summary

In this study, we aimed to compare serum PGRN(progranulin) and TNF-α levels in AS patients with healthy controls and to determine the relationship between TNF-α inhibitor use and PGRN levels in AS patients.

Who can participate

Age range20 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Between the ages of 20-65 * Signing the informed consent form * Axial spondyloarthropathy diagnosis according to ASAS 2009 criteria Exclusion Criteria: * Pregnancy or lactation * Having signs of acute or chronic infection * Presence of malignancy * Having concurrent secondary rheumatic disease other than Axial Spondyloarthropathy

What they're measuring

In this study, we aimed to compare serum PGRN and TNF-α levels in AS patients with healthy controls and to determine the relationship between TNF-α inhibitor use and PGRN levels in AS patients.

Timeframe: Patient will be seen only once

Trial details

NCT IDNCT07117344

SponsorKirsehir Ahi Evran Universitesi

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-07-30

Contact for this trial

Şeyda Sultan ERASLAN, MD

+905437676228 sultaneraslan353@gmail.com

View on ClinicalTrials.gov More Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA) trials