A study to evaluate the impact of nephrotic syndrome on the steady state pharmacokinetics and pharmacodynamics of edoxaban compared to health volunteers, and whether edoxaban can provide an equivalent anticoagulant effect to enoxaparin sodium.
Age range
18 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
area under the steady-state plasma concentration-time curve (AUCss)
Timeframe: Day 4 post-administation
time to peak (Tmax)
Timeframe: Day 4 post-administation
trough concentration at steady state (Css_min)
Timeframe: Day 4 post-administation
peak concentration at steady state (Css_max)
Timeframe: Day 4 post-administation
elimination half-life (t1/2)
Timeframe: Day 4 post-administation
average steady-state plasma concentration (Css_av)
Timeframe: Day 4 post-administation]
apparent volume of distribution (Vd/F)
Timeframe: Day 4 post-administation
clearance (CL/F)
Timeframe: Day 4 post-administation
anti-FXa activity
Timeframe: Day 4 post-administation
prothrombin time (PT)
Timeframe: Day 4 post-administation
activated partial thromboplastin time(APTT)
Timeframe: Day 4 post-administation
antithrombin Ⅲ(AT-III)
Timeframe: Day 4 post-administation
Protein C
Timeframe: Day 4 post-administation
Protein S
Timeframe: Day 4 post-administation
D-Dimer
Timeframe: Day 4 post-administation