The purpose of this study is to examine comparative effectiveness of two home-based telemedicine delivered interventions: transcranial Direct Current Stimulation (tDCS) combined with Massed Prolonged Exposure (Massed-PE) vs. Sham tDCS combined with Massed PE, focusing on pain and PTSD outcomes, to determine the comparative effectiveness of the two interventions on process outcomes of patient satisfaction, treatment attrition, and treatment compliance and to explore changes in blood biomarkers associated with stress and inflammatory processes related to pain and PTSD symptom improvements following treatment.
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Change in pain intensity as measured by the Defense and Veterans Pain Rating Scale (DVPRS)
Timeframe: Baseline, midpoint(before session 6), post treatment (after session 10) 3 months, 6 months
Change in PTSD symptoms as assessed by the Clinician-Administered PTSD Scale 5 (CAPS-5)
Timeframe: Baseline, post treatment (after session 10) 3 months, 6 months
Melba Hernandez-Tejada, PhD, DHA