CompletedNot Applicable

Clinical Efficacy of Chlorhexidine Varnish in Reducing Gingival Hyperplasia, Plaque Accumulation, and White Spot Lesions in Orthodontic Patients

Pakistan22 participantsStarted 2025-07-21

Plain-language summary

This study investigates whether applying a chlorohexidine varnish (a dental coating) reduces gum overgrowth, plaque buildup, and early tooth decay (white spots) in patients with braces. Each participant's mouth is divided into two sides: one receives the active varnish, and the other receives a placebo. Changes in gum health, plaque, and white spots are tracked over 3 months.

Who can participate

Age range15 Years – 30 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged 15-30 years * Subjects of both genders * Presence of permanent dentition Exclusion Criteria: * Craniofacial anomalies (cleft lip or palate) * Pregnant and lactating mothers * Patients at higher risk of drug allergies (antibiotics, anticoagulants, immunosuppressants, calcium channel blockers) * Allergy to any component of the varnishes * Mouth breathers

What they're measuring

Reduction in Gingival Hyperplasia

Timeframe: Baseline (T0) to 3 months (T3)

Trial details

NCT IDNCT07115784

SponsorKhyber Medical University Peshawar

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01-15

View on ClinicalTrials.gov More Gingival Hyperplasia trials