Symptom Distribution and Pain Sensitization in Carpal Tunnel Syndrome (NCT07114913) | Clinical Trial Compass
RecruitingNot Applicable
Symptom Distribution and Pain Sensitization in Carpal Tunnel Syndrome
Turkey (Türkiye)80 participantsStarted 2025-06-21
Plain-language summary
This study aims to compare central sensitization parameters between carpal tunnel syndrome (CTS) patients with extra median symptom distribution and those with typical, median nerve-related symptoms. Extra median sensory spread, observed in some CTS patients beyond the anatomical boundaries of the median nerve, may reflect central sensitization mechanisms. Using the Central Sensitization Inventory and pressure pain threshold measurements, this study will assess whether extra median symptom patterns are associated with increased central sensitization.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Having been diagnosed with carpal tunnel syndrome based on clinical and electrodiagnostic findings
* Being between 18 and 65 years of age
* Being literate
* Agreeing to participate in the study
Exclusion Criteria:
* Having a history of concomitant diabetes, systemic inflammatory disease, active infection, or malignancy
* Being \<18 and \>65 years of age
* Being illiterate
* Refusing to participate in the study
* Having a disease associated with neuropathic pain, such as polyneuropathy, radiculopathy, or multiple sclerosis
* History of injection or surgery for CTS within the last 6 months
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Pressure pain threshold
Timeframe: 3 months
2
Katz hand diagram
Timeframe: 3 months
Trial details
NCT IDNCT07114913
SponsorSultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey