CompletedEarly Phase 1

Pain Management in Teeth With Reversible Pulpitis

Turkey (Türkiye)46 participantsStarted 2025-08-02

Plain-language summary

Effective intraoperative pain management is vital in paediatric dentistry, especially during vital pulp therapy (VPT) for reversible pulpitis. Although NSAIDs are widely used postoperatively, their role in controlling pain during treatment is less understood. To investigate the effect of preoperative ibuprofen on pain perception and physiological stress during VPT in children.

Who can participate

Age range7 Years – 13 Years

SexALL

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Inclusion criteria

✓. Clinical and radiographic diagnosis of reversible pulpitis,
✓. Deep carious lesion extending beyond three-quarters of dentine thickness on periapical/bitewing radiographs (ICDAS score 5-6),
✓. Positive cold test response with Endo-Ice (Hygienic Corp., Akron, OH, USA) producing short-lasting pain (subsiding within \<10 seconds after stimulus removal),
✓. No clinical signs of swelling, abscess, or sinus tract,
✓. Absence of abnormal tooth mobility,
✓. Restorability of the tooth.

What they're measuring

Change in Pain Intensity From Baseline (Pre-Operative) to Immediately During the Procedure (Day 0), Measured by the Visual Analogue Scale (VAS)

Timeframe: Pre-Operative (Baseline) and Immediately During the Procedure (Day 0)

Trial details

NCT IDNCT07114198

SponsorInonu University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08-11

Results submitted2025-08-16

View on ClinicalTrials.gov More Reversible Pulpitis trials