A Study on the Efficacy of Environmental Probiotics in Patients With Cat Hair Allergies (NCT07114133) | Clinical Trial Compass
By InvitationNot Applicable
A Study on the Efficacy of Environmental Probiotics in Patients With Cat Hair Allergies
China100 participantsStarted 2025-06-30
Plain-language summary
Objective of this clinical trial:
The goal of this clinical study is to evaluate whether an environmental probiotic spray can improve symptoms in adults with cat allergy-induced allergic rhinitis (AR) and allergic asthma (AA). It will also assess the safety of the probiotic spray. The main questions it aims to answer are:
Does the environmental probiotic spray reduce the severity of nasal and asthma symptoms in participants? Are there any adverse effects observed in participants using the probiotic spray? Researchers will compare the environmental probiotic spray group to a placebo group (a look-alike spray containing no active ingredients) to determine if the probiotic spray is effective in managing allergic rhinitis and asthma symptoms.
Participants will:
Receive the environmental probiotic spray or placebo daily for 3 months Attend monthly clinic visits for checkups and assessments Undergo a final evaluation at 3 months, including symptom scoring and safety checks
Key Assessments:
Total Nasal Symptom Score (TNSS) for allergic rhinitis Asthma Control Test (ACT) score for allergic asthma
Who can participate
Age range
18 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18-70 years；
* Diagnosed with cat allergy (cat dander-specific IgE level ≥ class 2: \> 0.7 IU/mL) and allergic rhinitis with or without allergic asthma;
* Residing in the same living environment for at least 3 months (and no plans to change residence within the next 6 months);
* Patients receiving conventional symptomatic treatment.
Exclusion Criteria:
* Presence of other severe systemic diseases;
* Residence duration \< 3 months or plans to change residence within the next 6 months;
* Pregnancy;
* Current or planned use of biologic therapy;
* Any other condition that, in the investigator's judgment, may pose significant risks to the participant if enrolled in the study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change from Baseline in the TNSS score at 3 Months
Timeframe: 3 months
Trial details
NCT IDNCT07114133
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University