Autogenous Periosteal Pedicle Graft Versus Pericardium Membrane in Management of Periodontal Intrabony Defects in Stage III Periodontitis

Inclusion Criteria: * patients of both sexes aged (25-45) years old. * Patients who exhibit signs of (stage III) periodontitis. * Healthy individuals and free from systemic disease that may contraindicate periodontal surgery and influence the outcome of the therapy, according to the detailed questionnaire of the dental modification of the Cornell medical index . * Patients who have not received antibiotics or any medication for at least 6 months prior to this study. * Patients who have not undergone any type of Surgical periodontal therapy 6 months prior to the initial examination. * Patients able to return for multiple follow-up visits. Exclusion Criteria: * Pregnant and lactating females . * Teeth with mobility greater than Grade I according to Miller classification . * Patients with any harmful habits, like smoking or tobacco chewing. * Unacceptable oral hygiene after the re-evaluation of phase I therapy.