By InvitationNot Applicable

Implementation of Red Blood Cell Transfusion Recommendations in the Pediatric Intensive Care Unit

United States200 participantsStarted 2024-11-30

Plain-language summary

Evidence demonstrates that the risks of red blood cell transfusions outweigh benefits in many patients who are hospitalized in the pediatric intensive care unit with increased risk of organ dysfunction, infection, delirium, and death. Recommendations have been developed to restrict transfusion in patients who are unlikely to benefit; however, these recommendations have not been consistently adopted into clinical practice. This study examines use of targeted efforts (implementation strategies) to improve implementation of the recommendations, with a goal of reducing unnecessary transfusions and improving patient outcomes in critically ill children.

Who can participate

SexALL

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Inclusion Criteria: * Employed at Lucile Packard Children's Hospital at Stanford University or the Children's Hospital of Philadelphia AND * Employed in one of the following roles: * PICU nurse * PICU attending * PICU fellow * PICU resident * PICU advanced practice provider * Other physician or surgeon in subspecialties whose patients regularly receive transfusions in the PICU * PICU TRIP implementation team member * PICU nursing leader * PICU physician leader * Bood bank leader. Exclusion Criteria: * Unwilling to participate * Directly report to the primary investigator.

What they're measuring

Mean change from baseline in transfusion recommendation adherence at 18 months (evidence-based threshold alert)

Timeframe: 18 months

Trial details

NCT IDNCT07108374

SponsorStanford University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-31

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