Not Yet RecruitingNot Applicable

Assessment of Right Ventricular Function After Acute Pulmonary Embolism: a Comparison of Speckle Tracking Strain and Conventional Echocardiographic Parameters

Egypt100 participantsStarted 2025-09

Plain-language summary

Echocardiographic Assessment: Performed within 24h of PE diagnosis Conventional parameters: TAPSE, RV FAC, RV/LV ratio, tricuspid S', PASP STE parameters: RV free wall longitudinal strain (RVFWS), global longitudinal strain (GLS) if feasible All measurements averaged over 3 cardiac cycles (sinus) or 5 (AF) Follow-up data: ICU/hospital LOS Need for vasopressors/mechanical ventilation In-hospital and 30-day mortality

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Adults ≥18 years.
✓. Confirmed acute PE (via CT pulmonary angiography).(4,6)
✓. Echocardiography performed within 24 hours of diagnosis.

Exclusion criteria

✕. Pre-existing significant RV dysfunction (e.g., due to chronic pulmonary hypertension, cor pulmonale or congenital heart disease).
✕. History of coronary artery disease.
✕. Impaired LV systolic function, ejection fraction \<50%.
✕. Moderate to severe valvular heart disease.
✕. Prior document of an episode of pulmonary embolism.
✕. Poor acoustic window.
✕. Hemodynamic instability

What they're measuring

Primary (main): Composite of in-hospital mortality, ICU admission >7 days, or need for mechanical circulatory/ventilatory support.

Timeframe: 30 day follow up

Trial details

NCT IDNCT07107347

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-09

Contact for this trial

Doaa Roshdy, assistant lecturer

+201024588594 doaa.elenany@yahoo.com

View on ClinicalTrials.gov More Acute Pulmonary Embolism (PE) trials