Effects of Replacing High Protein Foods in People With Chronic Kidney Disease

Inclusion Criteria: * Age 40-70 years * Male or postmenopausal female * Stage 3 CKD (eGFR between 30-59ml/min/1.73m\^2 by the CKD-EPI equation (without race correction)). * If eGFR is greater than or equal to 45ml/min/1.73m\^2 then albuminuria must be greater than 300mg/g creatinine by spot urine. * Willing to consume controlled diet for duration of the study * Willing to collect fecal samples at home Exclusion Criteria: * Hemoglobin A1c greater than 7% within previous six months * Treatment with metformin or insulin within previous three months * Blood pressure greater than 150/100 mmHg from chart of home on at least two occasions in prior month (can be inclusive of screening visit) * Change in cardiovascular and/or hypertension medication in the last 30 days * History of major gastrointestinal disease (e.g. inflammatory bowel disease, uncontrolled irritable bowel syndrome, C. difficile chronic infection, celiac disease, diverticulitis, stomach or duodenal ulcers) * Known HIV disease * Hospitalization in the last two months * Significant recent unintentional weight loss (5% of weight over past three months) * Cancer or received cancer treatment in the last year (except basal cell carcinoma) * Prior bariatric surgery (i.e. gastric bypass, sleeve gastrectomy) or restrictive bariatric surgery (i.e. adjustable gastric band) * Treatment with immunosuppressive medications in the past six months or more than one week of treatment with prednisone greater than 10mg per day in the …