RecruitingNot Applicable

Food Intake and Thermogenesis in High Spinal Cord Injury

United States56 participantsStarted 2026-03-13

Plain-language summary

The purpose of this research is to determine the effects of food on cardiovascular and metabolic health in men with and without spinal cord injury (SCI).

Who can participate

Age range18 Years – 65 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: SCI and Controls * Men * Physically inactive (\<150 minutes per week of moderate-vigorous activity intensity for the preceding 3 months) * Weight stable: body mass ±3 kilograms (kg) for past 3 months SCI Only * Chronic SCI (≥ 1-year post-injury) * Motor-complete SCI American Spinal Injury Association Impairment Scale (AIS) A and B * T6 injuries and above that can independently feed themselves Exclusion Criteria: SCI and Controls * Uncompensated thyroid disease * Diabetes * Swallowing or gastrointestinal pathologies * Allergies or aversions to foods/ingredients * Prescribed prokinetic, antipsychotic, or anti-obesity agents SCI Only * Incomplete SCI AIS C or D * Ventilator-dependent

What they're measuring

Diet induced thermogenesis (DIT)

Timeframe: up to 3 weeks (collected during each of the intervention visits)

Hunger Series Visual Analog Scale

Timeframe: up to 3 weeks (collected during each of the intervention visits)

Post ad-libitum energy intake measured in grams

Timeframe: up to 3 weeks (collected during each of the intervention visits)

Trial details

NCT IDNCT07103993

SponsorUniversity of Miami

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-12-31

Contact for this trial

Guillermo Mederos

(305) 243-4518 gxm1228@med.miami.edu

View on ClinicalTrials.gov More SCI - Spinal Cord Injury trials