Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner

Inclusion Criteria: * Non-extraction cases * Complete permanent dentition * Good oral hygiene * Healthy periodontal condition * Single or double arch treatment * No therapeutic intervention planned intermaxillary or other intraoral or extraoral appliances including lip bumper, elastics and maxillary expansion appliances * mild to moderate crowding Exclusion Criteria: * Systemic medical conditions * Dental anomalies in tooth size or shape * Current use of anti-inflammatory medications