RecruitingNot Applicable

Postprandial Response to Fruit Juice

United States18 participantsStarted 2025-07-21

Plain-language summary

The goal of this clinical trial is to determine postprandial responses to fruit juices.

Age range18 Years – 45 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. ≥18 to ≤45 years of age at Visit 1.
✓. BMI ≥18.5 and \<30.0 kg/m2 at Visit 1.
✓. Fasting capillary glucose ≤110 mg/dL at Visit 1.
✓. Willing to avoid consuming high-polyphenol containing foods for 48 hours prior to each test visit.
✓. Willing to abstain from alcohol consumption for 24 hours prior to each study visit.
✓. Non-user of tobacco or nicotine products (e.g., cigarette smoking, vaping, chewing tobacco) within 12 months of Visit 1, with no plans to begin use during the study period.
✓. Non-habitual users (i.e., daily or almost daily) of marijuana or hemp products, including Cannabidiol (CBD)/Tetrahydrocannabinol (THC) products, and willing to abstain from use throughout the study period (topical creams/lotions are allowed).
✓. Willing to maintain habitual physical activity level throughout the duration of the study.

✕. History or presence of clinically important cardiac, renal, hepatic, endocrine, pulmonary, biliary, pancreatic, gastrointestinal, or neurological disorders that may affect the participant's ability to adhere to the study protocol and/or affect study outcomes, in the judgment of the Clinical Investigator.
✕. Uncontrolled hypertension (systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg) as defined by the blood pressure measured at Visit 1 (Section 9.1.1).
✕. Unstable use (initiation or change in dose) within 30 days of Visit 1 of antihypertensive medications.
✕. Unstable use (initiation or change in dose) within 30 days of Visit 1 of thyroid hormone replacement medications.
✕. Use of medications or supplements that may influence carbohydrate metabolism within 30 days of Visit 1.
✕. Extreme dietary habits (e.g., ketogenic, very high protein, very high fiber, vegan, vegetarian) at the discretion of the Clinical Investigator.
✕. Weight loss or gain \>4.5 kg in the 60 days prior to Visit 1.
✕. Currently, or planning to be, on a weight loss regimen during the study.

Blood glucose iAUC - 2 hours

Timeframe: 2 hours

NCT IDNCT07103083

SponsorOcean Spray Cranberries, Inc.

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2025-09-26

Kristen S Smith, PhD, RD

Who can participate

Age range18 Years – 45 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. ≥18 to ≤45 years of age at Visit 1.
✓. BMI ≥18.5 and \<30.0 kg/m2 at Visit 1.
✓. Fasting capillary glucose ≤110 mg/dL at Visit 1.
✓. Willing to avoid consuming high-polyphenol containing foods for 48 hours prior to each test visit.
✓. Willing to abstain from alcohol consumption for 24 hours prior to each study visit.
✓. Non-user of tobacco or nicotine products (e.g., cigarette smoking, vaping, chewing tobacco) within 12 months of Visit 1, with no plans to begin use during the study period.
✓. Non-habitual users (i.e., daily or almost daily) of marijuana or hemp products, including Cannabidiol (CBD)/Tetrahydrocannabinol (THC) products, and willing to abstain from use throughout the study period (topical creams/lotions are allowed).
✓. Willing to maintain habitual physical activity level throughout the duration of the study.

✕. History or presence of clinically important cardiac, renal, hepatic, endocrine, pulmonary, biliary, pancreatic, gastrointestinal, or neurological disorders that may affect the participant's ability to adhere to the study protocol and/or affect study outcomes, in the judgment of the Clinical Investigator.
✕. Uncontrolled hypertension (systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg) as defined by the blood pressure measured at Visit 1 (Section 9.1.1).
✕. Unstable use (initiation or change in dose) within 30 days of Visit 1 of antihypertensive medications.
✕. Unstable use (initiation or change in dose) within 30 days of Visit 1 of thyroid hormone replacement medications.
✕. Use of medications or supplements that may influence carbohydrate metabolism within 30 days of Visit 1.
✕. Extreme dietary habits (e.g., ketogenic, very high protein, very high fiber, vegan, vegetarian) at the discretion of the Clinical Investigator.
✕. Weight loss or gain \>4.5 kg in the 60 days prior to Visit 1.
✕. Currently, or planning to be, on a weight loss regimen during the study.