CompletedNot Applicable

Efficacy of Hyaluronidase Added to Bupivacaine in Ultrasound-guided Erector Spinae Plane Block in Percutaneous Nephrolithotomy.

Egypt100 participantsStarted 2025-01-01

Plain-language summary

Evaluation of the postoperative pain via numeric rating scale (NRS) through erector spinae plane block (ESPB) by adding hyaluronidase as an adjuvant to bupivacaine on the postoperative analgesia in erector spinae plane block.

Who can participate

Age range20 Years – 65 Years

SexALL

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Inclusion criteria

✓. Elective percutaneous nephrolithotomy
✓. Age: adult patients between 20 - 65 years old.
✓. Gender: Both male and female.
✓. ASA Class: I and II.

Exclusion criteria

✕. Refusal of patient.
✕. Patients ASA class III and IV.
✕. Chronic kidney disease grade lll \& lV .
✕. Pregnancy and lactation.
✕. Allergy to any of the study medications.
✕. Addicts and drug abusers.
✕. Patients taking corticosteroids or any cardio - active drugs.
✕. Severe coagulopathy ( INR \>3 or platelets \<70\*10) .

What they're measuring

Postoperative pain score by numeric rating scale (NRS)

Timeframe: Started measuring on admission to PACU ( 0 time) and 2, 4, 6 and 24 hours following admission

Trial details

NCT IDNCT07102771

SponsorKasr El Aini Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-10-30

View on ClinicalTrials.gov More Erector Spinae Plane Block, Nephrolithotomy, Hyaluronidase trials