In North America, up to 5% of preschoolers develop community-acquired pneumonia (CAP) every year. Pneumonia is the second-leading reason for paediatric hospitalization in both Canada and the US; approximately 20% of children hospitalized with CAP may need intensive care, which can result in significant morbidity. Given this burden of disease, it is critical that CAP is managed appropriately. Specific therapy for CAP is dependent on microbiologic aetiology, as bacterial disease will improve with antibiotic treatment.
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Antibiotic use for CAP or respiratory tract infection before day 7 post-enrolment
Timeframe: From enrollment to 7 days post enrollment
Early clinical response (ECR, clinical improvement in symptoms and lack of requirement for additional antibacterials as measured at day 4).
Timeframe: From enrollment to day 4