CompletedNot Applicable

Establishing Clinical Utility Evidence for a Novel Alzheimer's Disease Blood-Based Biomarker Assay

United States178 participantsStarted 2025-08-08

Plain-language summary

This is a national-level research study of neurologists and dementia specialists. The purpose of this study is to assess the clinical evaluation and management recommendations made by practicing providers for patient simulations with symptoms of cognitive decline.

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Board-certified in neurology for at least two years (and no more than 35 years * Average at least 20 hours per week of clinical and patient care duties over the past six months * Routinely evaluate patients at risk for Alzheimer's disease * Practicing in the United States * Able to read English * Access to the internet * Not participating in a clinical research study of the AD assay * Informed, signed, and voluntarily consented to participate in this study Exclusion Criteria: * Board-certified in neurology for less than two years * Board certification in neurology over 35 years ago * Unable to read English * Unable to access the internet * Not practicing in the United States * Not averaging at least 20 hours per week of clinical or patient care duties over the past six months * Participating in a clinical research study of the AD assay * Do not voluntarily consent to participate in this study

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

QURE virtual patient clinical score difference

Timeframe: Up to 12 months

Change in follow-up decisions (QURE scored-based) after receiving AD assay results

Timeframe: Up to 12 months

Trial details

NCT IDNCT07099001

SponsorQure Healthcare, LLC

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2025-12-31

View on ClinicalTrials.gov More Alzheimer Disease (AD) trials

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.