The aim of this study is to determine the incidence of myocardial injury after noncardiac surgery (MINS) in patients undergoing elective total knee or hip arthroplasty, and to identify the demographic, clinical, laboratory, and surgical risk factors that may contribute to its development.
Who can participate
Age range
45 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age over 45
* Elective total knee or hip replacement
Exclusion Criteria:
* Those undergoing cardiac surgery
* History of acute MI (\<30 days)
* Chronic elevation of troponin
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial studied myocardial injury — meaning heart muscle damage — that can happen after knee or hip replacement surgery, so should I get my heart evaluated before my joint replacement to understand my personal risk?
2Since this trial has already been completed, has my doctor seen any of its findings, and do those results change how my surgical or anesthesia team would monitor my heart during and after my procedure?
3The trial looked at anesthesia as a factor in heart injury after joint replacement — does the type of anesthesia I receive, such as general versus spinal, affect my risk of this kind of heart damage?
4Given that this study specifically measured ischemia-related heart damage after noncardiac surgery, what signs or symptoms should I watch for after my arthroplasty that might indicate my heart was affected?
5Are there standard pre-surgical screening steps or post-operative monitoring protocols that came out of research like this that my care team already uses, or would this be worth requesting as part of my care plan?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Ischemia-related myocardial damage after noncardiac surgery