The purpose of this research study is to compare two different combinations of anesthetic medications to see which works the best in providing the longest lasting pain relief for total knee arthroplasty surgery. The drugs being used are liposomal bupivacaine compared to a combination of bupivacaine, clonidine, epinephrine, buprenorphine, and dexamethasone. Pain scores will be collected at different intervals during study participation.
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Pain Score with Movement
Timeframe: Baseline
Pain Score with Movement
Timeframe: Hour 4 post final block placement
Pain Score with Movement
Timeframe: Hour 8 post final block placement