RecruitingNot Applicable

The PvCO2-PaCO2/CaO2-CvO2 Ratio in Septic Shock

Morocco30 participantsStarted 2025-01-05

Plain-language summary

The ratio of the venous-arterial carbon dioxide partial pressure difference to the arteriovenous oxygen content difference (Pv-aCO₂/Ca-vO₂) may be a marker of anaerobic metabolism in patients with acute circulatory failure. This study aims to assess the prognostic value of the PvCO2-PaCO2/CaO2-CvO2 in the early phase of septic shock.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Patients aged over 18 years presenting with septic shock, defined as sepsis with persistent hypotension requiring vasopressors to maintain a mean arterial pressure (MAP) ≥ 65 mmHg and lactatemia \> 2 mmol/L despite adequate fluid resuscitation. Sepsis is defined by the presence of a suspected or confirmed infectious source associated with organ dysfunction (neurological, respiratory, renal, hepatic, or hematological). \[Sepsis 3 criteria\] Exclusion Criteria: * Absence of central venous access. * Central venous access not positioned in the superior vena cava (e.g., femoral access).

What they're measuring

Prognostic value of PvCO2-PaCO2/Ca O2-CvO2 in patients with septic shock

Timeframe: From patient inclusion (baseilie = H0) then at H2, H6, H 12 and H24 (H = hours)

Trial details

NCT IDNCT07096284

SponsorAvicenna Military Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-06-30

Contact for this trial

Younes Aissaoui Professor of critical care medicine

+212661403332 younes.aissaoui@uca.ma

View on ClinicalTrials.gov More Septic Shock trials