By InvitationNot Applicable

Estimation of Cardiovascular Risk in Patients With Crohn's Disease and Ulcerative Colitis (PROVACI)

Italy600 participantsStarted 2025-02-07

Plain-language summary

Inflammatory bowel diseases (IBD) are progressively increasing their prevalence worldwide. Up to half of patients may also have extraintestinal manifestation and cardiovascular diseases (CVDs) is one of the most relevant, being the second cause of death in these patients. The classical cardiovascular (CV) risk scores do not adquately capture the CV risk in IBD. We are planning a prospective observational study to evaluate patients with IBD and a gender/age-matched cohort with the aims to investigate in 2-years follow-up * Occurrence of major cardiovascular events (MACEs) in both cohorts; * Predictive factors of risk for MACEs in IBD compared to controls; * Multi-omics evaluations with the support of artificial intelligence of biomarkers associated with occurrence of MACEs in IBD

Who can participate

Age range16 Years

SexALL

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Inclusion Criteria: Patients with confrimed diagnosis of Crohn's disease and Ulcerative colitis- Exclusion Criteria: No willing to sign the informe content and have 2 years of follow-up

What they're measuring

Occurrence of Major cardiovascular events

Timeframe: 2 years

Trial details

NCT IDNCT07095634

SponsorIRCCS Policlinico S. Donato

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-02

View on ClinicalTrials.gov More Ulcerative Colitis trials