Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva (NCT07095556) | Clinical Trial Compass
RecruitingNot Applicable
Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
United States39 participantsStarted 2025-11-05
Plain-language summary
The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation. Investigators plan to assess the impact of laser treatment on wound healing by measuring salivary biomarkers, gingival wound size and surveying for the use of pain reduction and patient satisfaction. The intervention group will receive extraction and alveolar ridge preservation with Nd-YAG laser photobiostimulation on days 1, 3, and 7 following extraction and socket preservation, while the control group will receive the standard of care extraction and alveolar ridge preservation without the laser
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Participants who are ≥ 18 years old,
* Patients who are scheduled for the treatment of tooth extraction and alveolar ridge preservation (ARP)
* No contraindications for tooth extraction and alveolar ridge preservation based on electronic health records.
* Participants who can express the level of pain
* Participants who self-report "not pregnant"
Exclusion Criteria:
* Untreated periodontal disease
* Acute infection of the teeth
* Use of antibiotics within the last three months.
* Pregnant or lactating women
* Use of bisphosphonates based on EHR
* Alveolar bone defects occurred or were detected during tooth extraction
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Inflammatory markers in saliva
Timeframe: From day of tooth extraction through day 7
2
Wound size dimensional changes
Timeframe: From the day of tooth extraction to day 42