A Comparative Study Between Neutrophil/Lymphocyte Ratio and Lactate/Albumin Ratio as Predictive I… (NCT07089524) | Clinical Trial Compass
RecruitingNot Applicable
A Comparative Study Between Neutrophil/Lymphocyte Ratio and Lactate/Albumin Ratio as Predictive Inflammatory Markers for Sepsis
Egypt160 participantsStarted 2024-09-11
Plain-language summary
Aim of this study is to predict the prognostic values of Neutrophil/ Lymphocyte ratio and Lactate/Albumin ratio in the outcome of patients with sepsis and septic shock with lower respiratory tract infection, also to compare between them regarding sensitivity and specificity.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults with lower respiratory tract infection
* Confirmed septic patients (under the third international consensus definitions of sepsis and septic shock),
* Admitted to intensive care unit.
* Age (18-80) years.
* Both genders.
Exclusion Criteria:
* Age: \< 18 years old, \> 80 years old
* Patient refusal.
* Pregnancy.
* Malignancy.
* Pathology that could affect serum albumin concentrations prior to ICU admission as Malnutrition
* Nephrotic syndrome
* Liver Cirrhosis
* Intestinal resection surgeries
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Detect the mortality due to sepsis with lower respiratory tract infection
Timeframe: From date of randomization until the date of death during the study period ( 12-18 months)
2
The prognostic values of Neutrophil/Lymphocyte ratio and Lactate/Albumin ratio in Sepsis
Timeframe: From date of randomization until the date of discharge from the ICU or death during the study period ( 12-18 months )