RecruitingNot Applicable

The Effectiveness of Dexmedetomidine as an Adjuvant for Bupivacaine Caudal Block in Pediatric Open Appendectomy Under General Anesthesia

Egypt60 participantsStarted 2025-08-01

Plain-language summary

This study aims to evaluate if adding dexmedetomidine to bupivacaine in a caudal block can provide longer and better quality pain relief for children after open appendectomy surgery. The study will also assess the effect of this combination on the quality of recovery, including the incidence of emergence delirium, and its overall safety profile.

Who can participate

Age range2 Years – 7 Years

SexALL

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inclusion criteria: * ASA (American Society of Anesthesiologists) physical status I or II. * Legal guardian provides written informed consent. Exclusion Criteria * Refusal of participation by the legal guardian. * Known allergy or hypersensitivity to local anesthetics or dexmedetomidine. * Coagulation disorder or receiving anticoagulant therapy. * Active infection at or near the injection site. * Significant anatomical abnormalities of the lumbosacral spine. * Pre-existing neurological disorders, psychiatric disorders, or a history of convulsions. * Anticipated surgery time of more than 2.5 hours. * Patients with severe asthma or active wheezing.

What they're measuring

Time to First Rescue Analgesia:

Timeframe: Up to 24 hours post-caudal block

Trial details

NCT IDNCT07088900

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-30

View on ClinicalTrials.gov More Appendectomy trials