The Clinical Study of Bone-patellar Tendon-bone and Quasi-anatomical Meniscus Allograft Transplan… (NCT07088094) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
The Clinical Study of Bone-patellar Tendon-bone and Quasi-anatomical Meniscus Allograft Transplantation Technique
200 participantsStarted 2025-08-01
Plain-language summary
This clinical study investigates the outcomes of bone-patellar tendon-bone and quasi-anatomical meniscus allograft transplantation techniques in patients requiring joint reconstruction. The study aims to assess the safety, efficacy, and functional improvements following these transplant procedures, utilizing donor tissues to restore joint function and alleviate pain in individuals with severe knee damage. Participants will undergo the transplantation procedure and be monitored for post-operative recovery, complications, and long-term outcomes, including joint stability and mobility. The study seeks to provide valuable insights into the effectiveness of these advanced surgical techniques for knee joint repair.
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 18-50 years
* Clinical diagnosis of symptomatic meniscal deficiency and anterior cruciate ligament injury (complete rupture or severe damage)
* Failure of conservative treatment (e.g., physical therapy, analgesia) for ≥6 months
* Stable knee joint (no ligamentous instability confirmed via clinical exam and MRI)
* Willingness to comply with postoperative rehabilitation and follow-up evaluations
Exclusion Criteria:
* Severe tibiofemoral osteoarthritis (Kellgren-Lawrence grade ≥3)
* History of prior knee infection or septic arthritis
* Inflammatory arthritis (e.g., rheumatoid arthritis, gout)
* BMI ≥35 kg/m²
* Pregnancy or planning pregnancy during the study period
* Concurrent full-thickness chondral defects (Outerbridge grade III-IV) in the affected compartment
* Inability to undergo MRI (e.g., claustrophobia, metallic implants)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of Postoperative Complications Unit of Measure
Timeframe: 2 years
2
Functional Improvement in Knee Joint Unit of Measure-Knee Society Score (KSS)
Timeframe: 2 years
3
Functional Improvement in Knee Joint Unit of Measure-Lysholm Knee Score