CompletedNot Applicable

Effect of Different Positive End-Expiratory Pressure (PEEP) Levels on Optic Nerve Sheath Diameter

Turkey (Türkiye)105 participantsStarted 2025-07-30

Plain-language summary

The goal of this prospective observational study is to evaluate the effects of different PEEP values on the optic nerve sheath diameter (ONSD), a noninvasive indicator of intracranial pressure (ICP), in patients undergoing vertebral surgery. The main question it aims to answer is how mechanical ventilation setting of 5 and 10 cmH2O PEEP effect optic nerve sheath diameter after surgery at extubation.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age between 18-65 years * ASA I, II, III * Patients undergoing elective vertebral surgery in the prone position Exclusion Criteria: * Patients were defined as having a hemoglobin concentration below 9 g/dL * Congestive heart failure * Uncontrolled hypertension * Severe COPD * Pulmonary edema * Cerebrovascular disease * Those who have had carotid stenosis or surgery * Hemodynamic instability * Pregnant women * Those who did not wish to participate in the study.

What they're measuring

Optic nerve sheath diameter measurement after extubation

Timeframe: just after extubation

Trial details

NCT IDNCT07085949

SponsorIzmir City Hospital

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2026-01-01

View on ClinicalTrials.gov More Optic Nerve Sheath Diameter trials