RecruitingNot Applicable

hAM for Inferior RRD

China50 participantsStarted 2025-08-01

Plain-language summary

The objective of the study is to evaluate the efficacy of using hAM patches over the retina to seal inferior retinal breaks. The researchers will evaluate whether hAM patch-assisted vitrectomy improves surgical success rate of retinal reattachment.

Who can participate

Age range

18 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Subjects having given free and informed consent to take part in the study.
. Subjects between 18 and 70 years old.
. Subjects suffering RRD (both primary and recurrent RRDs) with at least one of these conditions:
. inferior retinal breaks between 4- and 8-o'clock within the detached area regardless of PVR grade;
. requiring retinotomy inferiorly between 4- and 8-o'clock (due to severe inferior PVR or inferior retinal shortening).

Exclusion criteria

. Subjects with RRD with only anterior retina breaks or dialysis and meet the indications for scleral buckling surgery.
. Subjects with RRD whose retinal breaks located between the 4- and 8-o'clock positions and are not involved in the detached area.
. Subjects with pre-existing serious eye diseases (corneal ulcers, glaucoma, uveitis, etc).
. History of epilepsy or serious psychiatric diseases.
. Other conditions that the researcher found improper to be included into this study.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Retinal reattachment rate

Timeframe: From enrollment to the end of the 6-month follow-up period.

Visual acuity improvement

Timeframe: From enrollment to the end of the 6-month follow-up period.

Trial details

NCT IDNCT07081945

SponsorEye & ENT Hospital of Fudan University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-07-31

Contact for this trial

Zhongcui Sun, PhD.

+8621-64377134-2501 zhongcui.sun@aliyun.com

View on ClinicalTrials.gov More Rhegmatogenous Retinal Detachment trials