Active — Not RecruitingNot Applicable

Application of Pericapsular Nerve Group (PENG) Block

China68 participantsStarted 2025-07-12

Plain-language summary

This study aims to determine the efficacy and safety of the Pericapsular Nerve Group (PENG) block in preventing obturator nerve reflex during transurethral resection of bladder tumors.

Who can participate

Age range18 Years – 79 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged 18 years or older; * Scheduled for TURBT for unilateral bladder tumor; * Able to understand and provide informed consent; Exclusion criteria: * Patients who refuse or are unable to provide informed consent; * Allergic to local anesthetics, insensitive to propofol or general anesthetics; * Pregnant women; * Severe liver dysfunction; * Evidence of infection at or near the proposed puncture site; * Any sensory or motor impairment of the lower limbs; * Recent (within 6 months) lower limb joint replacement surgery.

What they're measuring

the percentage reduction in adductor muscle strength at 5, 10, 15, 20, 25, 30 minutes, and 3 hours after drug administration, compared to pre-administration levels.

Timeframe: 5, 10, 15, 20, 25, 30 minutes, and 3 hours post-administration

Trial details

NCT IDNCT07078773

SponsorNanjing First Hospital, Nanjing Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-31

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